Greetings! I am Spidikor.

I am an independent autodidactic neuropsychopharmacology researcher who has been teaching myself this material for a decade. I am interested in this topic at every level of magnification: I analyze the molecular dynamics of ion channels and receptors, their downstream intracellular signaling pathways, the structure and regional differences in function of neuroanatomy, and the macro-scale psychological and behavioral changes that result from manipulating these pathways. My goal is to elucidate the mechanisms that link these distinct layers of emergence.

‍ ‍A perfect example of this is my "canon event" Reddit post, in which I brought to light the finding that the mechanism of action of the neurogenic compound NSI-189 (aka Amdiglurax) is not, in fact, “unknown,” as almost every source claims. It is an agonist of the nuclear receptor TLX (aka NR2E1), as confirmed by early patent literature. Agonism at this receptor activates neural stem cells to grow and proliferate. My discovery explained the functional neurogenic effects of NSI-189 by revealing its target; the master regulator of neural stem cells, TLX. My discovery was the result of extensive internet sleuthing and mechanistic cross-referencing. These notes on NSI-189 and TLX serve as a representative example of the copious amount of effort I put into the work showcased on this site. They stand out as a proud achievement of mine.

‍ ‍As previously mentioned, I operate completely independently and without funding. I am not affiliated with any organization or academic institution, and have received no formal education on this subject. Rather, my research is self-directed and self-taught over the course of 10y. I am fueled by passion and driven by my insatiable curiosity. I have a strong desire to collect and share the information I learn, help people using said knowledge, and make friends along the way. If you are curious about my research, have a question, or just want to chat, feel free to shoot me a DM on Discord! I accept almost all friend requests, given they aren’t bots, and I’m always willing to help people out with personalized suggestions and detailed explanations, free of charge! Yes, that means you!

A bit more about me:
‍ ‍I have ADHD, Autism, Bipolar I, OCPD… the list goes on, but those ones are the most relevant to my showcased work. I feel that these overlapping phenotypes have strongly contributed to the shape of my work, and the fact I do any of this to begin with. After all, what neurotypical person decides to spend a decade teaching themself an extremely abstract topic like neuropsychopharmacology?
‍ ‍I am non-binary and use they/them pronouns. I have never felt any meaningful attachment to an internal gender, and have always felt… exempt from the concept. I have been living authentically as myself for 8y now. Social and hormonal transition have vastly improved my life and mental health and have enabled a high level of self-acceptance as well. I am aware that many in the biohacking and nootropics communities are uncomfortable with the trans and enby communities. But let’s face it. We are all biohackers here. You are allowed to experiment with novel research compounds with largely unknown safety profiles, but I am not allowed to biohack my gender? Come on. And for what reason other than gender affirmation do men use anabolic steroids? Think about it.
‍ ‍During my 8y authentically living as myself, I’ve heard every variation of the same old uninspired insults and alt-right talking points paraphrased from “alpha-male” podcasters. As stated previously, I am fully confident in who I am. I have a genuine sense of self-worth. But if you think you are the kind of person to be enraged by seeing an openly non-binary researcher, if you believe that you know me better than I know myself, if you are looking to “trigger the libs,” or to “debate” me in bad-faith about my own internal lived experiences, please know that I won’t bother engaging. I suggest you find a fulfilling hobby. I value my time, so I will not waste it by arguing with ignorant zealots who have no genuine intent to learn; I much prefer dedicating my time to research anyway.